- It comes from the blending of the two words brother and protein. It originated with my good friend from Clear Lake, TX saying brotein because of it’s funny similarity to protein. He thought it was funny that we both study biological sciences so we began using brotein for each other.
Brotein(2)
noun Blending
Brotein is another way to call someone your “bro” or brother.
Etymology : Blending of brother and protein. Brother is a native word and protein is a French term.
Source : “What up brotein, how are you?” –Eric November 2011
Last modified: 5 December 2011