The Rice University Neologisms Database

In MMORPG’s (massive multiplayer online role playing games), a long distance magical attack dealing a vast amount of damage over a very large dispersion range.The term is most likely used as a metaphor tying the video game version to the more traditional nuke, characterized by a devastating broad range weapon. However, it may also be an expansion of the meaning of the word nuke. Nuke originally referred to a nuclear powered explosive device. The meaning may have been expanded from this to include any very powerful explosive device, and then further to any devastating broad range weapon.